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Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

Interleukin 7 receptor, IL7R, is expressed exclusively on cells of the lymphoid lineage, and its expression is crucial for the development and maintenance of T cells. Alternative splicing of IL7R exon 6 results in membrane-bound (exon 6 included) and soluble (exon 6 skipped) IL7R isoforms. Interesti...

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Detalhes bibliográficos
Main Authors: Evsyukova, Irina, Bradrick, Shelton S., Gregory, Simon G., Garcia-Blanco, Mariano A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527722/
https://ncbi.nlm.nih.gov/pubmed/23151878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035410.112
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