Characteristics of Herpesvirus Mutants Resistant to Phosphonoformate and Phosphonoacetate

Mutants of herpes simplex virus type 1, resistant to phosphonoformate (PFA) and phosphonoacetate (PAA), have been selected in cell culture. The PFA-resistant mutant (HSV-PFA(r)) and the PAA-resistant mutant (HSV-PAA(r)) were also resistant to PAA and PFA, respectively. This cross-resistance indicate...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Eriksson, Bertil, Öberg, Bo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1979
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/475360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.6.758
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