Characteristics of Herpesvirus Mutants Resistant to Phosphonoformate and Phosphonoacetate

Mutants of herpes simplex virus type 1, resistant to phosphonoformate (PFA) and phosphonoacetate (PAA), have been selected in cell culture. The PFA-resistant mutant (HSV-PFA(r)) and the PAA-resistant mutant (HSV-PAA(r)) were also resistant to PAA and PFA, respectively. This cross-resistance indicate...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Eriksson, Bertil, Öberg, Bo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1979
Soggetti:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/475360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.6.758
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