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The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development
THO is a conserved eukaryotic complex involved in mRNP biogenesis and RNA export that plays an important role in preventing transcription- and RNA-mediated genome instability in mitosis and meiosis. In mammals THO is essential for embryogenesis, which limits our capacity to analyze the physiological...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527488/ https://ncbi.nlm.nih.gov/pubmed/23285047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052447 |
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