Hypothesis Testing and Power Calculations for Taxonomic-Based Human Microbiome Data

This paper presents new biostatistical methods for the analysis of microbiome data based on a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows the analyst to calculate power and sample sizes for experimental design, perform tests of hypotheses (e.g., compar...

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Hauptverfasser: La Rosa, Patricio S., Brooks, J. Paul, Deych, Elena, Boone, Edward L., Edwards, David J., Wang, Qin, Sodergren, Erica, Weinstock, George, Shannon, William D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527355/
https://ncbi.nlm.nih.gov/pubmed/23284876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052078
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