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Hypothesis Testing and Power Calculations for Taxonomic-Based Human Microbiome Data
This paper presents new biostatistical methods for the analysis of microbiome data based on a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows the analyst to calculate power and sample sizes for experimental design, perform tests of hypotheses (e.g., compar...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527355/ https://ncbi.nlm.nih.gov/pubmed/23284876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052078 |
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