Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice

BACKGROUND: Telmisartan is a well-established angiotensin II type 1 receptor blocker that improves insulin sensitivity in animal models of obesity and insulin resistance, as well as in humans. Telmisartan has been reported to function as a partial agonist of the peroxisome proliferator-activated rec...

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Bibliografske podrobnosti
Main Authors: Shiota, Asuka, Shimabukuro, Michio, Fukuda, Daiju, Soeki, Takeshi, Sato, Hiromi, Uematsu, Etsuko, Hirata, Yoichiro, Kurobe, Hirotsugu, Maeda, Norikazu, Sakaue, Hiroshi, Masuzaki, Hiroaki, Shimomura, Iichiro, Sata, Masataka
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527353/
https://ncbi.nlm.nih.gov/pubmed/23137106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-11-139
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