PTEN genomic deletion predicts prostate cancer recurrence and is associated with low AR expression and transcriptional activity

BACKGROUND: Prostate cancer (PCa), a leading cause of cancer death in North American men, displays a broad range of clinical outcome from relatively indolent to lethal metastatic disease. Several genomic alterations have been identified in PCa which may serve as predictors of progression. PTEN, (10q...

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Bibliografiske detaljer
Main Authors: Choucair, Khalil, Ejdelman, Joshua, Brimo, Fadi, Aprikian, Armen, Chevalier, Simone, Lapointe, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527151/
https://ncbi.nlm.nih.gov/pubmed/23171135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-543
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