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The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution

BACKGROUND: Proteins evolve at disparate rates, as a result of the action of different types and strengths of evolutionary forces. An open question in evolutionary biology is what factors are responsible for this variability. In general, proteins whose function has a great impact on organisms’ fitne...

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Autor principal: Alvarez-Ponce, David
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527147/
https://ncbi.nlm.nih.gov/pubmed/23020283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-192
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