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The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution

BACKGROUND: Proteins evolve at disparate rates, as a result of the action of different types and strengths of evolutionary forces. An open question in evolutionary biology is what factors are responsible for this variability. In general, proteins whose function has a great impact on organisms’ fitne...

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Detalhes bibliográficos
Autor principal: Alvarez-Ponce, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527147/
https://ncbi.nlm.nih.gov/pubmed/23020283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-192
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