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Investigating the Effects of a Hydrolytically Stable Hapten and a Th1 Adjuvant on Heroin Vaccine Performance

We challenged the performance of our previous heroin vaccine with a similar vaccine containing a more hydrolytically stable hapten analogue and a Th1 adjuvant (CpG ODN). Our results indicate that the elements of our previous vaccine are essential for its anti-heroin potency, i.e. a chemically labile...

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Bibliographic Details
Main Authors: Bremer, Paul T., Janda, Kim D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527012/
https://ncbi.nlm.nih.gov/pubmed/23134263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301262z
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