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Mechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinism

The role of amino acids in the regulation of insulin secretion in pancreatic beta-cells is highlighted in three forms of congenital hyperinsulinism (HI), namely gain-of-function mutations of glutamate dehydrogenase (GDH), loss-of-function mutations of ATP-dependent potassium channels, and a deficien...

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Détails bibliographiques
Auteurs principaux: Zhang, Tingting, Li, Changhong
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527006/
https://ncbi.nlm.nih.gov/pubmed/23212075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gms107
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