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Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell response by targeting the aminopeptidase ERAP1
The major histocompatibility complex (MHC) class I molecules present peptides on the cell surface by CD8(+) T cells, which is critical for killing of virally infected or transformed cells. Precursors of MHC class I-presented peptides are trimmed to mature epitopes by endoplasmic reticulum aminopepti...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526977/ https://ncbi.nlm.nih.gov/pubmed/21892175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2097 |
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