Dihydrofolate Reductase from Neisseria sp

Members of the genus Neisseria are relatively nonsusceptible to trimethoprim, an inhibitor of dihydrofolate reductase. For example, the minimal inhibitory concentration (MIC) of trimethoprim for N. gonorrhoeae ranges from 2 to 70 μg/ml, whereas the MIC for Escherichia coli is 0.2 μg/ml or less. In a...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Averett, Devron R., Roth, Barbara, Burchall, James J., Baccanari, David P.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1979
Fag:	Physiological Effects and Microbial Susceptibility
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/111611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.3.428
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