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Dihydrofolate Reductase from Neisseria sp

Members of the genus Neisseria are relatively nonsusceptible to trimethoprim, an inhibitor of dihydrofolate reductase. For example, the minimal inhibitory concentration (MIC) of trimethoprim for N. gonorrhoeae ranges from 2 to 70 μg/ml, whereas the MIC for Escherichia coli is 0.2 μg/ml or less. In a...

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Bibliografiske detaljer
Main Authors: Averett, Devron R., Roth, Barbara, Burchall, James J., Baccanari, David P.
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352677/
https://ncbi.nlm.nih.gov/pubmed/111611
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