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mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

BACKGROUND: The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors. There is a large body of experimental data on viral and cellular methyltransferases (MTas...

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Hlavní autoři: Bujnicki, Janusz M, Feder, Marcin, Radlinska, Monika, Rychlewski, Leszek
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC35267/
https://ncbi.nlm.nih.gov/pubmed/11472630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-2-2
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