mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

BACKGROUND: The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors. There is a large body of experimental data on viral and cellular methyltransferases (MTases) t...

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Pubblicato in:	BMC Bioinformatics
Autori principali:	Bujnicki, Janusz M, Feder, Marcin, Radlinska, Monika, Rychlewski, Leszek
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2001
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11472630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2105-2-2
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