Association of APOBEC3G genotypes and CD4 decline in Thai and Cambodian HIV-infected children with moderate immune deficiency

INTRODUCTION: Human APOBEC3G is a host defense factor that potently inhibits HIV replication. We hypothesize that HIV-infected children with a genetic variant of APOBEC3G will have a more rapid disease progression. METHODS: Antiretroviral therapy (ART)-naïve children, aged 1–12 years old with CD4 15...

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Main Authors: Bunupuradah, Torsak, Imahashi, Mayumi, Iampornsin, Thatri, Matsuoka, Kazuhiro, Iwatani, Yasumasa, Puthanakit, Thanyawee, Ananworanich, Jintanat, Sophonphan, Jiratchaya, Mahanontharit, Apicha, Naoe, Tomoki, Vonthanak, Saphonn, Phanuphak, Praphan, Sugiura, Wataru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526468/
https://ncbi.nlm.nih.gov/pubmed/23181827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-9-34
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