Antibody orientation at bacterial surfaces is related to invasive infection

Several of the most significant bacterial pathogens in humans, including Streptococcus pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable (Fc) region, and the dogma is that this protects the bacteria against phagocytic killing in blood. However, analysis of...

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Bibliographic Details
Main Authors: Nordenfelt, Pontus, Waldemarson, Sofia, Linder, Adam, Mörgelin, Matthias, Karlsson, Christofer, Malmström, Johan, Björck, Lars
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526361/
https://ncbi.nlm.nih.gov/pubmed/23230002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120325
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