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Antibody orientation at bacterial surfaces is related to invasive infection

Several of the most significant bacterial pathogens in humans, including Streptococcus pyogenes, express surface proteins that bind IgG antibodies via their fragment crystallizable (Fc) region, and the dogma is that this protects the bacteria against phagocytic killing in blood. However, analysis of...

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Autores principales: Nordenfelt, Pontus, Waldemarson, Sofia, Linder, Adam, Mörgelin, Matthias, Karlsson, Christofer, Malmström, Johan, Björck, Lars
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526361/
https://ncbi.nlm.nih.gov/pubmed/23230002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120325
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