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Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancy
Heterochromatin protein 1γ (HP1γ) is a chromatin protein involved in gene silencing. Herein, we show that HP1γ interacts with breast cancer type 1 susceptibility protein (BRCA1) and regulates BRCA1-mediated transcription via modulation of promoter occupancy and histone modification. We used several...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526311/ https://ncbi.nlm.nih.gov/pubmed/23074186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks947 |
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