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AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
Mutations in autoimmune regulator (AIRE) gene cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of peripheral-tissue antigens to mediate deletional tolerance, thereby preventing self-reactivi...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526288/ https://ncbi.nlm.nih.gov/pubmed/23074189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks933 |
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