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A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase—extensive moonlighting in mitochondrial tRNA biogenesis

Transfer RNAs (tRNAs) reach their mature functional form through several steps of processing and modification. Some nucleotide modifications affect the proper folding of tRNAs, and they are crucial in case of the non-canonically structured animal mitochondrial tRNAs, as exemplified by the apparently...

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Detalhes bibliográficos
Main Authors: Vilardo, Elisa, Nachbagauer, Christa, Buzet, Aurélie, Taschner, Andreas, Holzmann, Johann, Rossmanith, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526285/
https://ncbi.nlm.nih.gov/pubmed/23042678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks910
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