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Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex
SDR5C1 is an amino and fatty acid dehydrogenase/reductase, moonlighting as a component of human mitochondrial RNase P, which is the enzyme removing 5′-extensions of tRNAs, an early and crucial step in tRNA maturation. Moreover, a subcomplex of mitochondrial RNase P catalyzes the N(1)-methylation of...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446446/ https://ncbi.nlm.nih.gov/pubmed/25925575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv408 |
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