Randomized Controlled Phase Ib Study of Ghrelin Agonist, RM-131, in Type 2 Diabetic Women With Delayed Gastric Emptying: Pharmacokinetics and pharmacodynamics

OBJECTIVE: To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of single-dose RM-131 in type 2 diabetic patients with gastrointestinal cardinal symptoms (GCSI) and previously documented delayed gastric emptying (DGE). RESEARCH DESIGN AND METHODS: In a randomized crossover study, 1...

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Detalhes bibliográficos
Main Authors: Shin, Andrea, Camilleri, Michael, Busciglio, Irene, Burton, Duane, Stoner, Elizabeth, Noonan, Patrick, Gottesdiener, Keith, Smith, Steven A., Vella, Adrian, Zinsmeister, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526234/
https://ncbi.nlm.nih.gov/pubmed/22961573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-1128
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