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A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart
The transverse (t)-tubule system plays an essential role in healthy and diseased heart muscle, particularly in Ca(2+)-induced Ca(2+) release (CICR), and its structural disruption is an early event in heart failure. Both mechanical overload and unloading alter t-tubule structure, but the mechanisms m...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526164/ https://ncbi.nlm.nih.gov/pubmed/23100327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds434 |
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