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Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele
KitL, via its receptor cKit, supports primordial germ cell (PGC) growth, survival, migration and reprogramming to pluripotent embryonic germ cells (EGCs). However, the signaling downstream of KitL and its regulation in PGCs remain unclear. A constitutively activating mutation, cKit(V558Δ), causes ga...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526162/ https://ncbi.nlm.nih.gov/pubmed/23077213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds430 |
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