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Computational design of host transcription-factors sets whose misregulation mimics the transcriptomic effect of viral infections

The molecular mechanisms underlying viral pathogenesis are yet poorly understood owed to the large number of factors involved and the complexity of their interactions. Could we identify a minimal set of host transcription factors (TF) whose misregulation would result in the transcriptional profile c...

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Bibliografiske detaljer
Main Authors: Carrera, Javier, Elena, Santiago F.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525979/
https://ncbi.nlm.nih.gov/pubmed/23256040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01006
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