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Computational design of host transcription-factors sets whose misregulation mimics the transcriptomic effect of viral infections

The molecular mechanisms underlying viral pathogenesis are yet poorly understood owed to the large number of factors involved and the complexity of their interactions. Could we identify a minimal set of host transcription factors (TF) whose misregulation would result in the transcriptional profile c...

詳細記述

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書誌詳細
主要な著者: Carrera, Javier, Elena, Santiago F.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525979/
https://ncbi.nlm.nih.gov/pubmed/23256040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01006
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