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Hepatic mRNA, microRNA, and miR-34a-Target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation

Benzo(a)pyrene (BaP) is a mutagenic carcinogen that is ubiquitous in our environment. To better understand the toxic effects of BaP and to explore the relationship between toxicity and toxicogenomics profiles, we assessed global mRNA and microRNA (miRNA) expression in Muta™Mouse. Adult male mice wer...

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Detalhes bibliográficos
Main Authors: Malik, Amal I, Williams, Andrew, Lemieux, Christine L, White, Paul A, Yauk, Carole L
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525943/
https://ncbi.nlm.nih.gov/pubmed/21964900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20668
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