Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways

BACKGROUND AND PURPOSE: Pyrazole derivatives have recently been suggested as selective blockers of transient receptor potential cation (TRPC) channels but their ability to distinguish between the TRPC and Orai pore complexes is ill-defined. This study was designed to characterize a series of pyrazol...

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Hlavní autoři: Schleifer, H, Doleschal, B, Lichtenegger, M, Oppenrieder, R, Derler, I, Frischauf, I, Glasnov, TN, Kappe, CO, Romanin, C, Groschner, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525873/
https://ncbi.nlm.nih.gov/pubmed/22862290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02126.x
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