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Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways

BACKGROUND AND PURPOSE: Pyrazole derivatives have recently been suggested as selective blockers of transient receptor potential cation (TRPC) channels but their ability to distinguish between the TRPC and Orai pore complexes is ill-defined. This study was designed to characterize a series of pyrazol...

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Detalhes bibliográficos
Main Authors: Schleifer, H, Doleschal, B, Lichtenegger, M, Oppenrieder, R, Derler, I, Frischauf, I, Glasnov, TN, Kappe, CO, Romanin, C, Groschner, K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525873/
https://ncbi.nlm.nih.gov/pubmed/22862290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02126.x
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