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Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries

BACKGROUND AND PURPOSE: Calcitonin gene-related peptide (CGRP) is a potent vasodilator, implicated in the pathogenesis of migraine. CGRP activates a receptor complex comprising, calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1). In vitro studies indicate recyc...

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書誌詳細
主要な著者: McNeish, AJ, Roux, BT, Aylett, S-B, Van Den Brink, AM, Cottrell, GS
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525870/
https://ncbi.nlm.nih.gov/pubmed/22881710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02129.x
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