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Evidence for Conversion of 5-Fluorocytosine to 5-Fluorouracil in Humans: Possible Factor in 5-Fluorocytosine Clinical Toxicity

A gas chromatographic-mass spectrometric method for detecting 5-fluorouracil (5-FU) in serum at concentrations as low as 10 ng/ml was used to determine to what extent 5-FU was present in the serum of patients taking oral 5-fluorocytosine (5-FC). Preliminary studies in two patients and two healthy vo...

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Hlavní autoři: Diasio, Robert B., Lakings, Duane E., Bennett, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1978
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC352577/
https://ncbi.nlm.nih.gov/pubmed/742878
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