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Synergy of topical Toll-Like Receptor 7 agonist with radiation and low dose cyclophosphamide in a mouse model of cutaneous breast cancer

PURPOSE: This study tested the hypothesis that topical Toll-Like Receptor (TLR) 7 agonist imiquimod promotes anti-tumor immunity and synergizes with other treatments in a model of skin-involving breast cancer. EXPERIMENTAL DESIGN: TSA mouse breast carcinoma cells were injected s.c. into syngeneic mi...

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Detalhes bibliográficos
Main Authors: Dewan, M. Zahidunnabi, Vanpouille-Box, Claire, Kawashima, Noriko, DiNapoli, Sara, Babb, James S., Formenti, Silvia C., Adams, Sylvia, Demaria, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525760/
https://ncbi.nlm.nih.gov/pubmed/23048078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0984
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