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Autochthonous T cells to the rescue: IL-10 directly activates tumor-resident CD8(+) T cells
Successful cancer immunotherapy is thought to require de novo priming of tumor specific CD8(+) T cells in lymphatic organs. Contrasting these beliefs, cancer therapy based on interleukin-10 (IL-10) results in tumor rejection without a requirement for T-cell trafficking from lymphatic organs. Rather,...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525629/ https://ncbi.nlm.nih.gov/pubmed/23264920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21683 |
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