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Killing from within

Interleukin-10 (IL-10) is considered to be an immunosuppressive cytokine. However, the continuous administration of pegylated IL-10 (PEG-IL10) leads to the rejection of large, firmly established and metastatic syngeneic tumors. PEG-IL10 therapy induces the expansion and activation of intratumoral, t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mumm, John B., Emmerich, Jan, Oft, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525615/
https://ncbi.nlm.nih.gov/pubmed/23264906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21423
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