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Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction
Myeloid-derived suppressor cells (MDSCs), identified as Gr1(+)CD11b(+) cells in mice, expand during cancer and promote tumor growth, recurrence and burden. However, little is known about their role in bone metastases. We hypothesized that MDSCs may contribute to tumor-induced bone disease, and inocu...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525604/ https://ncbi.nlm.nih.gov/pubmed/23264895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21990 |
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