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Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

Pharmacogenetics enables personalised therapy based on genetic profiling and is increasingly applied in drug discovery. Medicines are developed and used together with pharmacodiagnostic tools to achieve desired drug efficacy and safety margins. Genetic polymorphism of drug-metabolising enzymes such...

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Detalhes bibliográficos
Main Authors: Matimba, Alice, Del-Favero, Jurgen, Van Broeckhoven, Christine, Masimirembwa, Collen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525272/
https://ncbi.nlm.nih.gov/pubmed/19164093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-3-2-169
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