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Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects
Pharmacogenetics enables personalised therapy based on genetic profiling and is increasingly applied in drug discovery. Medicines are developed and used together with pharmacodiagnostic tools to achieve desired drug efficacy and safety margins. Genetic polymorphism of drug-metabolising enzymes such...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525272/ https://ncbi.nlm.nih.gov/pubmed/19164093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-3-2-169 |
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