Whole genome DNA copy number changes identified by high density oligonucleotide arrays

Changes in DNA copy number are one of the hallmarks of the genetic instability common to most human cancers. Previous micro-array-based methods have been used to identify chromosomal gains and losses; however, they are unable to genotype alleles at the level of single nucleotide polymorphisms (SNPs)...

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Hlavní autoři: Huang, Jing, Wei, Wen, Zhang, Jane, Liu, Guoying, Bignell, Graham R, Stratton, Michael R, Futreal, P Andrew, Wooster, Richard, Jones, Keith W, Shapero, Michael H
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525261/
https://ncbi.nlm.nih.gov/pubmed/15588488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-1-4-287
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