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Whole genome DNA copy number changes identified by high density oligonucleotide arrays

Changes in DNA copy number are one of the hallmarks of the genetic instability common to most human cancers. Previous micro-array-based methods have been used to identify chromosomal gains and losses; however, they are unable to genotype alleles at the level of single nucleotide polymorphisms (SNPs)...

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Main Authors: Huang, Jing, Wei, Wen, Zhang, Jane, Liu, Guoying, Bignell, Graham R, Stratton, Michael R, Futreal, P Andrew, Wooster, Richard, Jones, Keith W, Shapero, Michael H
格式: Artigo
語言:Inglês
出版: BioMed Central 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525261/
https://ncbi.nlm.nih.gov/pubmed/15588488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-1-4-287
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