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Effects of Trehalose Polycation End-group Functionalization on Plasmid DNA Uptake and Transfection

In this study, we have synthesized six analogs of a trehalose-pentaethylenehexamine glycopolymer (Tr4) that contain (1A) adamantane, (1B) carboxy, (1C) alkynyl-oligoethyleneamine, (1D) azido trehalose, (1E) octyl, or (1F) oligoethyleneamine end groups and evaluated the effects of polymer end group c...

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Autors principals: Anderson, Kevin, Sizovs, Antons, Cortez, Mallory, Waldron, Chris, Haddleton, D.M., Reineke, Theresa M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524837/
https://ncbi.nlm.nih.gov/pubmed/22616977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300471n
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