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Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent

BACKGROUND: Sigma receptors are highly expressed in human tumors and should be appropriate targets for developing tumor imaging agents. Previously, we synthesized a vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino]cyclohexanol ((+)-pIV), with a high affinity for sigma receptors and prepared radio...

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Detalhes bibliográficos
Main Authors: Ogawa, Kazuma, Kanbara, Hiroya, Shiba, Kazuhiro, Kitamura, Yoji, Kozaka, Takashi, Kiwada, Tatsuto, Odani, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524758/
https://ncbi.nlm.nih.gov/pubmed/23021206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-54
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