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Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
BACKGROUND: Sigma receptors are highly expressed in human tumors and should be appropriate targets for developing tumor imaging agents. Previously, we synthesized a vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino]cyclohexanol ((+)-pIV), with a high affinity for sigma receptors and prepared radio...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524758/ https://ncbi.nlm.nih.gov/pubmed/23021206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-54 |
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