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Subtle alterations in breathing and heart rate control in the 5-HT(1A) receptor knockout mouse in early postnatal development

We hypothesized that absence of the 5-HT(1A) receptor would negatively affect the development of cardiorespiratory control. In conscious wild type (WT) and 5-HT(1A) receptor knockout (KO) mice, we measured resting ventilation (V̇e), oxygen consumption (V̇o(2)), heart rate (HR), breathing and HR vari...

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Detalhes bibliográficos
Main Authors: Barrett, Karlene T., Kinney, Hannah C., Li, Aihua, Daubenspeck, J. Andrew, Leiter, James C., Nattie, Eugene E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524655/
https://ncbi.nlm.nih.gov/pubmed/22936722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00939.2012
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