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Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. We previously showed that Perilipin 2 (Plin2), a member of lipid droplet protein family, is markedly increased in fatty liver, and its reduction in the liver of diet-induced obese mice by antisense oligonucleotide (...

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Detalhes bibliográficos
Main Authors: Imai, Yumi, Boyle, Siobhan, Varela, Gladys M., Caron, Emilie, Yin, Xiaoyan, Dhir, Raina, Dhir, Ravindra, Graham, Mark J., Ahima, Rexford S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524651/
https://ncbi.nlm.nih.gov/pubmed/23012396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00045.2012
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