Effects of Hypoxemia upon Aminoglycoside Serum Pharmacokinetics in Animals

Hypoxemia causes significant alterations in aminoglycoside serum pharmacokinetics in adult rats and newborn rabbits. The aminoglycoside serum clearances were diminished in hypoxemic animals. Comparisons of intravenous and intramuscular administration imply a delay in uptake of drug from intramuscula...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mirhij, Najwa J., Roberts, Robert J., Myers, Martin G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1978
Assuntos:	Pharmacology and Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/708011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.3.344
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