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C-Myc Induced Compensated Cardiac Hypertrophy Increases Free Fatty Acid Utilization for the Citric Acid Cycle

The protooncogene C-Myc (Myc) regulates cardiac hypertrophy. Myc promotes compensated cardiac function, suggesting that the operative mechanisms differ from those leading to heart failure. Myc regulation of substrate metabolism is a reasonable target, as Myc alters metabolism in other tissues. We hy...

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Autori principali: OLSON, AARON K., LEDEE, DOLENA, IWAMOTO, KATE, KAJIMOTO, MASAKI, PRIDDY, COLLEEN O’KELLY, ISERN, NANCY, PORTMAN, MICHAEL A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524362/
https://ncbi.nlm.nih.gov/pubmed/22828478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.07.005
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