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DNA damage, chromatin, and transcription: the trinity of aging
Aging brings about numerous cellular defects. Amongst the most prominent are elevated levels of persistent DNA damage, changes to chromatin structure and epigenetic modifications, and alterations of global transcription programs. These are not independent events and recent work begins to shed light...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524355/ https://ncbi.nlm.nih.gov/pubmed/22902297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.07.005 |
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