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QUANTIFICATION OF A GASTROINTESTINAL SODIUM CHANNELOPATHY

Na(v)1.5 sodium channels, encoded by SCN5A, have been identified in human gastrointestinal interstitial cells of Cajal (ICC) and smooth muscle cells (SMC). A recent study found a novel, rare missense R76C mutation of the sodium channel interacting protein telethonin in a patient with primary intesti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yong Cheng, Poh, Beyder, Arthur, Strege, Peter R., Farrugia, Gianrico, Buist, Martin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524340/
https://ncbi.nlm.nih.gov/pubmed/21959314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.09.014
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