Učitavanje...

Carbenoxolone Treatment Ameliorated Metabolic Syndrome in WNIN/Ob Obese Rats, but Induced Severe Fat Loss and Glucose Intolerance in Lean Rats

BACKGROUND: 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) regulates local glucocorticoid action in tissues by catalysing conversion of inactive glucocorticoids to active glucocorticoids. 11β-HSD1 inhibition ameliorates obesity and associated co-morbidities. Here, we tested the effect of 11β-...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Prasad Sakamuri, Siva Sankara Vara, Sukapaka, Mahesh, Prathipati, Vijay Kumar, Nemani, Harishankar, Putcha, Uday Kumar, Pothana, Shailaja, Koppala, Swarupa Rani, Ponday, Lakshmi Raj Kumar, Acharya, Vani, Veetill, Giridharan Nappan, Ayyalasomayajula, Vajreswari
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524236/
https://ncbi.nlm.nih.gov/pubmed/23284633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050216
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!