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Ser2481-autophosphorylated mTOR colocalizes with chromosomal passenger proteins during mammalian cell cytokinesis

Energy- and nutrient-sensing proteins such as AMPK, mTOR and S6K1 are now recognized as novel regulators of mitotic completion in proliferating cells. We investigated the cellular distribution of the Ser2481 autophosphorylation of mTOR, which directly monitors mTORC-specific catalytic activity, duri...

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Detalhes bibliográficos
Main Authors: Vazquez-Martin, Alejandro, Sauri-Nadal, Tamara, Menendez, Octavio J., Oliveras-Ferraros, Cristina, Cufí, Sílvia, Corominas-Faja, Bruna, López-Bonet, Eugeni, Menendez, Javier A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524217/
https://ncbi.nlm.nih.gov/pubmed/23095638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22551
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